The processes of angiogenesis and neurogenesis show striking similarities. Given our strong roots in providing Neuroscience research reagents, it is a natural extension for us to provide potent reagents for the studying the growth of new blood vessels.
Angiogensis processes are important for healing wounds and for restoring blood flow to tissues after injury or insult. In females, it also occurs during the monthly reproductive cycle and during pregnancy(to build the placental circulation between mother and fetus.
Images: Increased arteriogenesis and hyperemia in TSP2-null mice. Smooth muscle actin-positive and ephrin B2-positive vessels in WT (F, H) and TSP2-null (G, I). DOI: 10.2353/ajpath.2008.080128.
Angiogenesis-dependent diseases result when new blood vessels either grow excessively or insufficiently. These disease include: cancers, diabetic blindness, age-related macular degeneration, rheumatoid arthritis, psoriasis, neurodegeneration and many more.
|Angiogenic Growth Factors||Endothelial Cell Markers|
|Ephs/Ephrins||ILs, CCRs, CXCs, MIPs and STATs|
|Intra-Cellular Signaling-Angiogenesis||Matrix Metalloproteinases (MMPs)|
|Other Angiogenesis Research Antibodies||RayBio® C-Series Human Angiogensis Arrays|
Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays-Agiogenesis
|Semaphorins and Plexins||Wnts/FZDs/Dkks|