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Type: Rat IgG
 
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: M
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Protein G Purified - liquid
 
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a rat immunized with purified, Sf 21-derived recombinant mouse Agouti-Related Protein (rmAgRP).
 
Description/Data:

Agouti-related Protein (AgRP), also known as the protein product of the agouti-related transcript (ART), is a neuropeptide and a functional antagonist of alpha-MSH on MC-3 and MC-4 receptors, both of which are implicated in obesity. AgRP shares sequence and structural homology with the Agouti protein and has similar expression patterns in both mouse and human.

It is also supsected to play a role in modulation of pain.

Image: Agouti-related Protein (AgRP) expression was detected in a cryostat section of mouse brain. The tissue was stained using the NorthernLights-637 anti-rat IgG secondary antibody ( red) and counterstained with FluoroNissl™ Green (green).