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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| MO15101 | 100 ug | $255.00 | Buy Now | Add to Cart |
Type: Mouse IgG
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: H; Pr
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Protein G Purified - liquid
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human Renin proform (rhRenin pro; Accession # P00797; aa 24 – 406).
Description/Data:
Renin is a secreted aspartyl protease that plays a crucial role in the regulation of blood pressure and salt balance through the cleavage of angiotensinogen, the only known physiological substrate of Renin. Renin is expressed as a precursor consisting of a signal sequence (aa 1 - 23), a propeptide (aa 24 - 66), and a mature chain (aa 67 - 406). The amino acid sequence of human REN is 100%, 73%, 71% and 67% identical to that of chimpanzee, canine, mouse and rat.
Image: Renin Propeptide was detected in paraffin-embedded human kidney glomerulus sections using 15 µg/ml mouse anti-human Renin monoclonal antibody. Tissue was subjected to antigen retrieval, stained using anti-mouse HRP-DAB (brown), and counterstained with hematoxylin (blue).