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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| RA25034 | 100 ul | $265.00 | Buy Now | Add to Cart |
Type: Rabbit IgG
Applications: IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images; ; HPLC=High Performance Liquid Chromatography; FPLC=Fast Protein Liquid Chromatography
Species Reactivity: M; R
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
Immunogen: Synthetic peptide made to a C-terminal portion of the rat protein (within residues 1430-1508). [Swiss-Prot# Q5G856].
Description/Data:
TRPM2 is a member of the melastatin-related TRPM subfamily belonging to the transient receptor potential or TRP channel superfamily. TRPM2 can form a Ca2+-permeable cationic channel activated by intracellular ADP-ribose. The physiological functions of TRPM2 remain largely unknown except that activation of TRPM2 channel can initiate yet unidentified signalling cascades that lead to membrane disruption and eventually cell death.
Image: TRPM2 (red) and GFAP (green) staining of rat hippocampus. Nclei staining is blue. Image courtesy of Dr. Ji-Zhong Bai, The University of Auckland, New Zealand.
Related antibodies to consider:
VR1 (TRPV1) - mouse specific (RA14113)
Image: Detection of TRPM2. Lane 1: CHO cells untransfected. Lane 2: CHO cell transfected with rat TRPM2 Lane 3: Mouse cortical neurons (cultured). Photo courtesy of Dr. Paco Herson, Oregon Health & Science University.