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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| RA25040 | 100 ul | $385.00 | Buy Now | Add to Cart |
Type: Rabbit IgG
Applications: ICC; IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: M; R
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Whole serum - lyophilized
Immunogen: Synthetic peptide (Rat) from the N-terminal extracellular domain conjugated to immunogenic carrier protein.
Description/Data:
Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.
Image:Factor Inhibiting HIF1 staining of rat brain tissue (dilution: 1:100).
Image: Detection of Factor Inhibiting HIF-1 by Western Blot.
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Apoptosis Research Reagents -Apoptosis Categories-includes: detection kits, antibodies and proteins.