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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| MO18005 | 400 ul | $275.00 | Buy Now | Add to Cart |
Type: Mouse IgG
Applications: IHC
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Protein G Purified - liquid
Immunogen: Produced by immunizing BALB/c mice with stimulated human leukocytes.
Description/Data:
CD45 antigen is a protein which is a leucocyte common antigen, a type I transmembrane protein present on all differentiated hematopoietic cells except erythrocytes that assists in the activation of those cells (a form of co-stimulation). It is expressed in lymphomas, B-cell chronic lymphocytic leukemia, hairy cell leukemia, and acute nonlymphocytic leukemia.
Studies have shown that expression of CD 45 is elevated in microglia in AD brain compared with controls.
Image: CD45 staining of paraffin-embedded human tonsil.