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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| PR15053-10 | 10 ug | $295.00 | Buy Now | Add to Cart |
Type: Protein
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Description/Data:
Dopa decarboxylase (DDC), also known as aromatic amino acid decarboxylase, is a group II decarboxylase.(3) The enzyme catalyzes the decarboxylation of aromatic L-amino acids to produce the corresponding amines. DDC produces the neurotransmitters dopamine and serotonin from L-Dopa and L-5-hydroxytryptophan, respectively. The inhibition of DDC could be used for the treatment of schizophrenia and Parkinson's disease.(4)
References:
1. Ichinose, H. et al., 1989, Biochem. Biophys. Res. Comm. 164:1024 - 1030.
2. Sherald, F. et al., 1973, Anal. Biochem. 56:300 - 305.
3. Sandmeier, E. et al., 1994, Eur. j. Biochem. 221:997 - 1002.
4. Bertoldi, M. et al., 1996, J. Biol. Chem. 271:23954 - 23959.