|Catalog Number||Size||Price (USD)||Shopping Cart|
|MO22145||100 ul||$295.00||Buy Now | Add to Cart|
Tau is a relatively low molecular weight member of the microtubule associated protein or MAP. The recombinant protein used to make this antibody is the shortest version of the 8 human tau proteins, so the antibody is expected to bind to all 8 isoforms.
Tau is heavily concentrated in axons of neurons, but may also be found in dendrites and in some non neuronal cells. Much interest has focused on tau as it is a major component of the neurofibrillary tangles of Alzheimer’s disease .
Image: E18 hippocampal neurons were grown for seven days following the protocol. We fixed and immunostained with MO22145 (green) using our standard immunostaining protocol (on datasheet), chicken antibody to α-internexin (CH22101 red) and for DNA (blue). MO22145 stains the neuronal perikarya and process strongly, and does not stain non neuronal cells in these cultures. The α-internexin antibody stains intermediate or 10nm filament bundles in the cytoplasm of these cells.