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GT41015100 ug$250.00   $310.00Buy Now | Add to Cart
 
Type: Goat IgG
 
Applications: IHC; E
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: Synthetic peptide: Peptide with sequence: TSLPLGVKVEDS-C, from the N Terminus of the protein sequence according to NP_002439.1.
 
Description/Data:
Picture

MSX1 is a transcriptional repressor that belongs to the Msh homeobox family. It plays a role in cranofacial development and, via a onic hedgehog-controlled cascade that includes MSX1 acts in parallel with the Wnt1 network, establishes the midbrain dopaminergic progenitor domain, which gives rise to a neuronal population that is critical for normal function of the human brain. It is an excellent marker for this population of neural progenitors.

Pathologies in dopaminergic neurons result in a number of neurological diseases inclusing Parkinson's Disease.

Image: MSX1 staining of staining of paraffin embedded Human Prostate(dilution: 2.5µg/ml). Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Protocol on data-sheet.