|Catalog Number||Size||Price (USD)||Shopping Cart|
|GT41015||100 ug||$250.00 $310.00||Buy Now | Add to Cart|
MSX1 is a transcriptional repressor that belongs to the Msh homeobox family. It plays a role in cranofacial development and, via a onic hedgehog-controlled cascade that includes MSX1 acts in parallel with the Wnt1 network, establishes the midbrain dopaminergic progenitor domain, which gives rise to a neuronal population that is critical for normal function of the human brain. It is an excellent marker for this population of neural progenitors.
Pathologies in dopaminergic neurons result in a number of neurological diseases inclusing Parkinson's Disease.
Image: MSX1 staining of staining of paraffin embedded Human Prostate(dilution: 2.5µg/ml). Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Protocol on data-sheet.