GDF-5

Affinity Purified Goat Antibody

DATASHEET (pdf - 217Kb)

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Type: Goat IgG

Applications: IHC; WB; E

ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;

Species Reactivity: M

B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins

Format: Affinity Purified - liquid

Immunogen: Purified, E. coli-derived, recombinant mouse growth differentiation factor 5 (rmGDF-5).

Description/Data:

Growth differentiation factors (GDF-1 to GDF-15) are members of the bone morphogenetic protein (BMP) family, within the transforming growth factor beta (TGF-beta) superfamily. GDF-5, -6, and -7 share 80-86% aa sequence identity with each other and define a subgroup within the BMP family. GDF-8 is most closely related to GDF-11 with 90% aa sequence identity. Similarly to the other members of this family, the GDFs are highly conserved across species (with the possible exception of GDF-15).

Image: GDF-5 staining of cryostat tissue sections E-12 of mouse embryos. Tissues were stained with anti-goat HRP-DAB (brown)and Haematoxylin (blue) counterstain.

Other Reagents to Consider: