GDNF Receptor Alpha 1

Mouse Monoclonal Antibody

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Type: Mouse IgG

Applications: IHC; WB; E

ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;

Species Reactivity: R

B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins

Format: Protein G Purified - liquid

Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant rat GDNF family receptor alpha 1 (rrGFR alpha-1) extracellular domain.

Description/Data:

GDNF, Neurturin, Artemin, and Persephin are distant members of the TGF-beta superfamily that function as neurotrophic factors. Their bioactivities are mediated by a receptor complex composed of the non-ligand-binding signaling subunit (c-Ret receptor tyrosine kinase) and one of four ligand binding subunits designated GFR alpha-1 through 4, which are cysteine-rich glycosyl-phosphatidylinositol (GPI)-linked cell surface proteins.

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GDNF Receptor Alpha 1

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