Brain Derived Growth Factor (BDNF) promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the cns. the versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (ltp), long-term depression (ltd), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. New Testimonial: "I am replying on behalf on Joan Han, who you sent an email to regarding our purchase of BDNF, CF. We have successfully utilized your BDNF in our experiments. Thank you for checking in." Chiew-Jen Ong, NIH.