Delta Opioid Receptor 361-372

Affinity Purified Rabbit Antibody
DATASHEET(pdf - 79Kb)
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Type: Rabbit IgG
 
Applications: IF; IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H; M; R
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Immunogen: Synthetic peptide comprising residues 361-372 TPSDGPGGGAAA of the human DOR-1 protein.
 
Description/Data:
Picture

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that activate intracellular signaling cascades and undergo endocytosis, recycling, or degradation upon stimulation.  The (mu) m-, delta (d) and kappa (k) opioid receptors are GPCRs of the nervous system, which control pain, stress, and addictive behaviors.  The delta opioid receptor (DOR-1) is the stereoselective receptor for enkephalins and inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance


Image: Western blot analysis with DOR at a dilution of 1:500. Lane 1: 10 ug of human brain lysate, Lane 2: 10 ug rat brain lysate and Lane 3: 10 ug rat brain lysate

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