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RA13105100 ul$295.00Buy Now | Add to Cart
P1310550 ul @ 1 mgs/ml Blocking Peptide$175.00Buy Now | Add to Cart
 
Type: Rabbit IgG
 
Applications: ICC; IHC; WB
E=ELISA; FC=Flow Cytometry; ICC=Immunocytochemistry; IF=Immunofluorescence; IP=Immunoprecipitation; IHC=Immunohistochemistry; SE=Sandwich ELISA; WB=Western blotting; NB=Neutralization of Bioactivity; FACS; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; BSM=Biosactive Small Molecule or Peptide; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; AC=Adherent Cell Assays; NAC=Non-adherent Cell Assays; CDM=Cell Differentiation Media; BSC-CM5= Biacore Sensor Chip CM5; FM=Fluorescent Micsroscopy; ; ; ; ; ; ; ; ; ; ; Health and Fitness
Species Reactivity: M; R
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: AAPPQNENAEDAK
 
Description/Data:
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Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

IHC Image: Staining of mouse nob rescue retinal sections.  

WB Image: Mouse retinal lysates. Courtesy of Megan A. Foreman, University of Birmingham.

mGluR6-Customer Data and Publications.

Note: A customer found a band in the 60-70 kDa range corresponding to the mGluR6 precursor.

 

Picture[3]

Image: mGluR6 staining of GluR6 in trapezoid body in mouse brain using anti-rabbit Cy3 conjugated secondary antibodies (red color). DAPI was used to counterstain cell nuclei. Dilution 1:30. Tissue was mounted to slide using i-BRITE Plus anti fade media.

 

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