|Catalog Number||Size||Price (USD)||Shopping Cart|
|RA13105||100 ul||$295.00||Buy Now | Add to Cart|
|P13105||50 ul @ 1 mgs/ml Blocking Peptide||$175.00||Buy Now | Add to Cart|
Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
IHC Image: Staining of mouse nob rescue retinal sections.
WB Image: Mouse retinal lysates. Courtesy of Megan A. Foreman, University of Birmingham.
Metabotropic Glutamate Receptors (mGluRs)- mGluR1 alpha-mGluR6/7
Neurotransmission Research Antibodies -GPCRs, Ligand Gated Ion Channels, Biogenic Amines and more
Primary Neurons and Astrocytes -Primary human, rat and mouse neurons and astrocytes by Category
Image: mGluR6 staining of GluR6 in trapezoid body in mouse brain using anti-rabbit Cy3 conjugated secondary antibodies (red color). DAPI was used to counterstain cell nuclei. Dilution 1:30. Tissue was mounted to slide using i-BRITE Plus anti fade media.
Image: mGluR6 (green) and protein kinase C (green) staining of P100 rat retinas. (mGluR6 dilution 1:2000). Raymond D. Lund, Shaomei Wang, Bin Lu, Sergej Girman, Toby Holmes, Yves Sauvé, Darin J. Messina, Ian R. Harris, Anthony J. Kihm, Alexander M. Harmon, Feng-Yi Chin, Anna Gosiewska, Sanjay K. Mistry. Cells Isolated from Umbilical Cord Tissue Rescue Photoreceptors and Visual Functions in a Rodent Model of Retinal Disease. Stem Cells Vol. 25 No. 3 March 2007, pp. 602 -611 doi:10.1634/stemcells.2006-0308; www.StemCells.com © 2007 AlphaMed Press