SOX17

Affinity Purified Goat Antibody
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Type: Goat IgG
 
Applications: ICC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Description/Data:
Picture

The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate.

SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development.

Image: SOX17 staining of  endodermal cells derived from human embyronic stem cells. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody  and counterstained using Fluoro Nissl (green). Courtesy of Dr. Jong-Hoon Kim and Dr. Ron McKay from the National Institute of Neurological Disorders and Stroke & Stem Cell Unit at NIH.

For flow cytometry using SOX 17 see: SBDR - SOCIETY FOR BIOMEDICAL DIABETES RESEARCH
Turning Human Epidermis Into Pancreatic Endoderm.

Sox17: Customer Publications

More Links:

SOX Antibodies

Endodermal Lineage Markers

STEMEZ (TM) Human Neural Progenitor & Neuron Discovery Kits

Stem Cell Research Reagents

 

Picture[2]

Image: SOX17 protein is present in various maturation stages of spermatogenesis: spermatogonium (black arrow), secondary spermatocyte (white arrow), and spermatid (black arrowhead), while primary spermatocytes, spermatozoa, and Sertoli cells are negative. 10.1002/path.2332. Copyright © 2008 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.