CD31/PECAM-1

Affinity Purified Sheep Antibody
DATASHEET(pdf - 173Kb)
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Type: Sheep IgG
 
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Immunogen: Purified, CHO cell-derived, recombinant human CD31 (rhCD31) extracellular domain.
 
Description/Data:
Picture

The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions, on T cell subsets, and to a lesser extent, on platelets and most leukocytes. CD31 is required for the transendothelial migration of leukocytes through the intercellular spaces between vascular endothelial cells.

 

Image: CD31 staining of paraffin-embedded human breast cancer tissue sections. (dilutions 5 µg/mL). Tissues were stained using anti-sheep HRP-DAB (brown-red) and counterstained with hematoxylin (blue).

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