Caspase 3, activeData Courtesy of Ramaswamy Sharma and Dr. Alexander Gow, Wayne State University |
Image: Immunostaining for activated caspase-3 (red) and proteolipid protein (PLP1) in the cortex of P16 msd/Y mutant mouse. Inset shows DAPI staining for nuclei (top), PLP1 (middle) and activated caspase-3 (bottom).
msd mouse reference: Gow A, Southwood CM, Lazzarini RA. Disrupted proteolipid protein trafficking results in oligodendrocyte apoptosis in an animal model of Pelizaeus-Merzbacher disease. J.Cell Biol. 1998 Feb 23;140(4):925-34.