Caroline Chamberland, Hector Barajas-Martinez, Volker Haufe, Marie-Hélène Fecteau, Jean-Francois Delabre, Alexander Burashnikov, Charles Antzelevitch, Olivier Lesur, Ahmed Chraibi, Philippe Sarret and Robert Dumaine. Modulation of canine cardiac sodium current by Apelin. Journal of Molecular and Cellular Cardiology. Volume 48, Issue 4, April 2010, Pages 694-701

...Primary rabbit anti-APJ-R antibody (1:2000; Neuromics, US)...

Klára Farkasfalvi, Mark A. Stagg, Steven R. Coppen, Urszula Siedlecka, Joon Lee, Gopal K. Soppa, Nándor Marczin, István Szokodi, Magdi H. Yacoub and Cesare M.N. Terracciano. Direct effects of apelin on cardiomyocyte contractility and electrophysiology. doi:10.1016/j.bbrc.2007.04.017.

...rabbit anti-APJ, affinity purified antiserum, Neuromics, MN, US...

Nils W. G. Lambrecht, Iskandar Yakubov, Cindy Zer and George Sachs Transcriptomes of purified gastric ECL and parietal cells: identification of a novel pathway regulating acid secretion
Physiol. Genomics 25: 153-165, 2006

...anti-APJ receptor monoclonal antibody (Neuromics)

The gastric entero-chromaffin-like (ECL) cell plays a key regulatory role in peripheral regulation of acid secretion due to the release of histamine that stimulates acid secretion by the parietal cell. Studies in intact animals, gastric glands, and isolated cells after short-term culture have shown expression of stimulatory CCK2 and PAC1 and inhibitory SST2 and Gal1 receptors as well as histidine decarboxylase. However, the pattern of its gene expression as a neuroendocrine cell has not been explored. Comparison of gene expression by 95% pure ECL cells obtained by density gradient, elutriation, and fluorescence-assisted cell sorting with isolates of the intact fundic gastric epithelium (i.e., "subtractive hybridization") identified a variety of additional expressed gene families characteristic of this neuroendocrine cell. These include genes 1) involved in neuropeptide synthesis and secretory vesicle exocytosis, 2) involved in control of inflammation, 3) implicated in healing of the epithelium, 4) encoding inhibitory Gi protein-coupled receptors, 5) playing a role in neuroendocrine regulation of food intake, and 6) encoding proteins likely involved in maintenance of circadian rhythm, in addition to the ECL cell-specific genes histidine decarboxylase and monoamine transporter. Particularly, the inhibitory apelin receptor gene, APJ, was highly expressed in the ECL cell preparation. Because parietal cells express apelin, immunohistochemical and functional studies showed that there is an inhibitory feed back loop between the parietal and ECL cell during gastrin stimulation, providing evidence for a novel pathway of downregulation of acid secretion due to interaction between these two cell types.