Orphanin FQ/Nociceptin-Guinea Pig
Primary Neurons and Astrocytes -Primary human, rat and mouse neurons and astrocytes
Andrew C. Eschenroeder, Allison A. Vestal-Laborde, Emilse S. Sanchez, Susan E. Robinson, Carmen Sato-Bigbee. Oligodendrocyte responses to buprenorphine uncover novel and opposing roles of μ-opioid- and nociceptin/orphanin FQ receptors in cell development: Implications for drug addiction treatment during pregnancy. Glia Volume 60, Issue 1, pages 125–136, January 2012.
Dmitry Gerashchenko, Tamas L. Horvath, Xinmin (Simon) Xie. Direct inhibition of hypocretin/orexin neurons in the lateral hypothalamus by nociceptin/orphanin FQ blocks stress-induced analgesia in rats. Neuropharmacology, Volume 60, Issue 4, March 2011, Pages 543-549.
Xinmin Xie1, Jonathan P. Wisor, Junko Hara, Tara L. Crowder, Robin LeWinter, Taline V. Khroyan, Akihiro Yamanaka, Sabrina Diano, Tamas L. Horvath, Takeshi Sakurai, Lawrence Toll and Thomas S. Kilduff. Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. Published in Volume 118, Issue 7 (July 1,2008). J. Clin. Invest. 118(7): 2471-2481 (2008). doi:10.1172/JCI35115. Copyright © 2008, American Society for Clinical Investigation.
...Brain sections (10 μm) were treated with 0.3% H2O2 to quench endogenous peroxidases and then incubated overnight in primary anti-N/OFQ (1:5,000; RA10106, anti-FGGFTGARKSARKLANQ, Neuromics)...
Chad D. Foradori, Marcel Amstalden, Lique M. Coolen, Sushma R. Singh, Christine J. McManus, Robert J. Handa, Robert L. Goodman and Michael N. Lehman. Orphanin FQ: Evidence for a Role in the Control of the Reproductive Neuroendocrine System. Endocrinology, doi:10.1210/en.2007-0011
...OFQ (1:3000, Neuromics)...