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GT15068100 ug$365.00Buy Now | Add to Cart
 
Type: Goat IgG
 
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: M
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Immunogen: Recombinant mouse Endostatin
 
Description/Data:
Picture

Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis.

Endostatin eliminated tumors in mice. Researchers reported that the proteins eliminated forms of colon, prostate, breast and brain cancers in the animal experiments. Endostatin also appears to block new blood vessel growth in tumors blocking the metastatic process.

Image: Endostatin staining in mouse brain.