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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| RA25007 | 100 ul | $255.00 | Buy Now | Add to Cart |
Type: Rabbit IgG
Applications: IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
Immunogen: A C-terminal synthetic peptide made to the human LRRK2 protein sequence (between residues 2500-2527).
Description/Data:
Lrrk2 (Leucine rich repeat kinase 2 antibody), PARK8, Dardarin or ROCO2 is is a member of the leucine-rich repeat kinase family. Variants of this gene are associated with an increased risk of Parkinson's disease and also Crohn's disease.
Four LRRK2 gene variants found are found in a third of Parkinson’s cases, but infrequent in the general population. Unexpectedly, genomewide association studies have found an association between LRRK2 and Crohn's disease as well, suggesting that the two diseases share common pathways
Image: Mouse CAD cells transfected with Human wild-type LRRK-2 (1:2,000).