Glycine Receptor

Whole Serum-Rabbit Antibody
DATASHEET(pdf - 181Kb)
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Type: Rat IgG
 
Applications: IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H; R
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Whole serum - lyophilized
 
Description/Data:
Picture

The glycine receptor (GlyR) chloride channel is a member of the nicotinic acetylcholine receptor family of ligand-gated ion channels. Its glycine-mediated activation results in an influx of chlorine ions that hyperpolarize and desensitize neuronal postsynaptic membranes. There are at least five GlyR subunits (four alpha-type and one beta-type) that form homo- or heteromultimers. Alpha1-beta multimers may be the principal synaptic GlyR in adults.

Image: Western blot of 10 μg of rat spinal cord. As shown in the autoradiograph, the Anti-Glycine Receptor antibody is specific for the ~48 kDa subunits recognizing both the α1 and α2 subunits of the Glycine Receptor.

Other Reagents to Consider:

Antibodies:

Autism/Asperger's Syndrome

Neurodegenerative Disease

IL; CCR and CXCs 

Proteins:

Neurodegenerative Disease

Interleukins