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GT15043100 ug$365.00Buy Now | Add to Cart
GT1504350 ug$89.00   $215.00Buy Now | Add to Cart
 
Type: Goat IgG
 
Applications: E; IHC; WB
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: Recombinant human Parkin isoform 2
 
Description/Data:
Picture

Parkin-1 and 2 contain an N-terminal ubiquitin-like domain, a linker region, and a C-terminal TRIAD domain consisting of two RING finger motifs flanking a cysteine-rich IBR motif. Mutations in Parkin are a major cause of autosomal recessive juvenile Parkinsonism. Parkin-2 lacks exon 5 which encodes amino acid residues 179 - 206 of Parkin.

Image: Parkin-2 (Parkin isoform 2) staining of paraffin-embedded Human Cerebellum tissue sections.  Tissues were stained using anti-goat HRP-DAB (brown) and counterstained with Haematoxylin (blue). Dilution: 15 µg/mL.