|Catalog Number||Size||Price (USD)||Shopping Cart|
|GT41023||100 ug||$265.00 $335.00||Buy Now | Add to Cart|
|P41023||100 ug Blocking Peptide||$145.00||Buy Now | Add to Cart|
Laforin is encoded bt the EMP2A gene and plays a critical role in the survival of neurons in the brain. Laforin is also expressed in many other cells throughout the body and has mutliple functions. To carry out these functions, laforin interacts with several other proteins, including malin (which is produced from the NHLRC1 gene). These proteins are part of complex networks that transmit chemical signals and break down unneeded or abnormal proteins.
Image: Laforin (dilution: 2.8 µg/ml) staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Protocol on data-sheet.
Mutations in the EPM2A gene lead to the major features of Lafora progressive myoclonus epilepsy. Additionally, laforin may act as a tumor suppressor protein.
Apoptosis Research Reagents-includes: detection kits, antibodies and proteins
Primary Neurons and Astrocytes-Primary human, rat and mouse neurons and astrocytes
Image: Laforin (dilution: 0.1µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.