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RA19000100 uL$250.00Buy Now | Add to Cart
 
Type: Rabbit IgG
 
Applications: WB
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: LLLLTSEIDLPVKRRA (a.a. 9-24 of Humanin peptide)
 
Description/Data:
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Humanin (HN) encodes a polypeptide that appears to protect neurons from both cytotoxic and apoptotic cell death in Alzheimer’s disease.  Analogues of the HN peptide have been shown to spare memory in animal models of Alzheimer’s, suggesting its potentially important therapeutic role.   It is found in highest levels in testis, colon, and AD-affected brain tissues.

 

We currently have tested the antibody by Western blotting against the human HN peptide and cell lysates of 293T cells transfected with a GFP tagged HN.