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GT15113100 ug$365.00Buy Now | Add to Cart
 
Type: Goat IgG
 
Applications: ICC; IHC; WB; E
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: M
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: Recombinant mouse TNF alpha
 
Description/Data:
Picture

Tumor necrosis factor alpha (TNF-alpha), also called cachectin, is produced by many normal and tumor cells in response to a wide variety of stimuli, including viruses, bacteria, parasites, cytokines and mitogens. In solution, TNF-alpha is a trimeric molecule. Both the transmembrane and the soluble, secreted forms of TNF-alpha are biologically active. TNF-alpha is an extremely pleiotropic cytokine due to the ubiquity of its receptors, to its ability to activate multiple signal transduction pathways and its ability to induce or suppress the expression of a wide number of genes.

Image: TNF-alpha staining of  immersion fixed activated mouse T Cells at 15 µg/mL for 3 hours at room temperature (red) and counterstained (green).