|Catalog Number||Size||Price (USD)||Shopping Cart|
|MO15024||100 ug||$255.00||Buy Now | Add to Cart|
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the class I cytokine receptor family. Binding of IL-6 (IL-11) to either the membrane-anchored or soluble IL-6 R (IL-11 R) initiates the association of IL-6 R (IL-11 R) with gp130, which then undergoes homo-dimerization and signal transduction. With other IL-6 family cytokines, such as LIF and OSM, signal transduction is triggered by the hetero-dimerization of gp130 and LIF R or OSM R.
Please note: this antibody has been referenced for use in IHC for mouse DRGs (dilution 1:50). see: J. Neurosci., Oct 2009; 29: 13473 - 13483 ; doi:10.1523/JNEUROSCI.1822-09.2009.
antibodies: proteins: Primary Neurons and Astrocytes -Primary human, rat and mouse neurons and astrocytes
proteins:Leukemia Inhibitory Factor (LIF), human
Primary Neurons and Astrocytes -Primary human, rat and mouse neurons and astrocytes