Type: Mouse IgG
Applications: IHC; WB; E
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Protein G Purified - liquid
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human T cell Immunoglobulin and mucin-domain-containing molecule 1 (rhTIM-1) extracellular domain. Clone: 219211
Members of the TIM family are type I transmembrane glycoproteins. All share a characteristic extracellular region containing immunoglobulin V-like and mucin domains. TIM proteins are reported to have multiple immune system functions including regulating T cell differentiation, T cell effector function, allergies, and autoimmune disease. It is suspected to play a role in Rheumatoid
Image: TIM-1 was detected in paraffin-embedded human kidney tubule sections. Tissue was stained using HRP-DAB (brown) and counterstained with hematoxylin (blue).
Other Reagents to Consider:
CD and Cell Surface Markers
IL; CCR and CXCs
Pain and Inflammation
Image: Detection of TIM-1. Human kidney or ovary tissue extracts were prepared in reducing sample buffer, resolved by SDS-PAGE and transferred to an Immobilon-P membrane. The blot was developed with 2 μg/mL MAB1750 using chemiluminescent detection. 25 μg total protein was loaded per lane.