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Type: Goat IgG
 
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: M
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Immunogen: Purified, NS0-derived, recombinant mouse Frizzled-4 (rmFrizzled-4) extracellular Cysteine-Rich Domain (CRD).
 
Description/Data:
Picture

Frizzled 4, also known as FZD4 and CD344,  is a neuronal stem cell marker. This includes expression on fetal neuronal progenitor cells and neuronal intestinal cells. Transcripts have also been identified in liver, kidney, pancreas, spleen, and fetal lung, and in smaller amounts in placenta, adult lung, prostate, testis and colon.

It has been reported that it controls retinal and inner ear angiogenesis, participates in the regulation of embryonic development, tissue and cell polarization and proliferation.

Image:FZD4 staining of E18 Mouse Neuronal Tissue.  Tissue was stained with goat HRP-DAB (brown) and counterstained with Hematoxylin (blue). Dilution: 15 µg/mL.