Matrix Metalloproteinases (MMPs)
Matrix Metalloproteinases (MMPs) are a family of zinc metalloendopeptidases secreted by cells, and are responsible for much of the turnover of matrix components. They are produced as zymogens, with a signal sequence and propeptide segment that must be removed during activation. In general, This signal sequence and propeptide plus a catalytic domain (containing the highly conserved zinc binding site) characterizes the structure of the MMPs.
MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer's, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.
Image: Matrix Metalloproteinase 14 (MMP-14) staining of human testis.
|ADAM10 (Human)||GT15078||Goat IgG||H||E; IHC; WB||100 ug||$365|
|ADAM10 (Mouse)||GT15079||Goat IgG||M||IHC; WB||100 ug||$365|
|Matrix Metalloproteinase 2 (MMP-2, Gelatinase A)||RA22107||Rabbit IgG||H; R||IF; IHC; WB||100 ul||$295|
|Matrix Metalloproteinase 9 (MMP-9)||GT15020||Goat IgG||M; R||ICC; IHC; WB; IP; E||100 ug||$365|
|Matrix Metalloproteinase 14 (MMP-14)||RA30020||Rabbit IgG||H||IHC; WB; E||50 ug||$365|
|Matrix Metalloproteinase 24 (MMP-24, MT5-MMP)-Human||RA15045||Rabbit IgG||H||IHC; WB||50 ug|