Matrix Metalloproteinases (MMPs) are a family of zinc metalloendopeptidases secreted by cells, and are responsible for much of the turnover of matrix components. They are produced as zymogens, with a signal sequence and propeptide segment that must be removed during activation. In general, This signal sequence and propeptide plus a catalytic domain (containing the highly conserved zinc binding site) characterizes the structure of the MMPs.

MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer's, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.

Image: Matrix Metalloproteinase 14 (MMP-14) staining of human testis.  

NameCatalog #TypeSpeciesApplicationsSizePrice
ADAM10 (Human)GT15078Goat IgGHE; IHC; WB100 ug$365
ADAM10 (Mouse)GT15079Goat IgGMIHC; WB100 ug$365
Matrix Metalloproteinase 2 (MMP-2, Gelatinase A)RA22107Rabbit IgGH; RIF; IHC; WB100 ul$295
Matrix Metalloproteinase 9 (MMP-9)GT15020Goat IgGM; RICC; IHC; WB; IP; E100 ug$365
Matrix Metalloproteinase 14 (MMP-14)RA30020Rabbit IgGHIHC; WB; E50 ug$365
Matrix Metalloproteinase 24 (MMP-24, MT5-MMP)-HumanRA15045Rabbit IgGHIHC; WB50 ug
100 ug