Network with Neuromics
Contact Information
Neuromics
5325 West 74th St., Suite 8
Edina, MN 55439
Toll free: 866-350-1500
Int'l phone: 952-374-6161
Fax: 612-677-3976
|
| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| GT15078 | 100 ug | $365.00 | Buy Now | Add to Cart |
Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE.
Image: ADAM10 staining of paraffin-embedded human prostate cancer tissue. Tissues were stained Goat HRP-DAB (red-brown) and counterstained with hematoxylin (blue).