Matrix Metalloproteinase 3 (MMP-3/Stromelysin1)

Affinity Purified Rabbit Antibody

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RA30021	50 ug	$365.00	Buy Now \| Add to Cart

Type: Rabbit IgG

Applications: IHC; WB; IP; E

ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;

Species Reactivity: H; R

B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins

Format: Affinity Purified - liquid

Immunogen: Peptide from the N-terminus of active human MMP3.

Description/Data:

Matrix Metalloproteases (MMPs) play important roles in many physiological or pathological processes including embryonic development, morphogenesis, reproduction, tissue remodeling, arthritis, cancer and cardiovascular disease.

MMP3 is an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP3 is reported to be implicated in rheumatoid arthritis and some forms of cancer.

Image: MMP3 staining of human muscle: Formalin-Fixed Paraffin-Embedded (FFPE).

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