Matrix Metalloproteinase 14 (MMP-14)

Affinity Purified Rabbit Antibody

DATASHEET (pdf - 221Kb)

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Type: Rabbit IgG

Applications: IHC; WB; E

ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;

Species Reactivity: H

B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins

Format: Affinity Purified - liquid

Immunogen: Synthetic Peptide- Amino acids 160 to 173 of human MMP14.

Description/Data:

Matrix Metalloproteases (MMPs) play important roles in many physiological or pathological processes including embryonic development, morphogenesis, reproduction, tissue remodeling, arthritis, cancer and cardiovascular disease.

MMP14 may be an activator of pro gelatinase A and is expressed in fibroblast cells during both wound healing and human cancer progression. MMP14 is expressed in very low levels and may require stimulation with concanavolin A or the phorbol ester TPA to stimulate production of MMP14.

Image: MMP staining of human lung: Formalin-Fixed Paraffin-Embedded (FFPE).

Other Reagents to Consider:

All Matrix Metalloproteinase Antibodies

Cancer Antibodies

Neurodegenerative Disease Antibodies

Pain and Inflammation

Apoptosis Research Reagents