|Catalog Number||Size||Price (USD)||Shopping Cart|
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Agouti-related Protein (AgRP), also known as the protein product of the agouti-related transcript (ART), is a neuropeptide and a functional antagonist of alpha-MSH on MC-3 and MC-4 receptors, both of which are implicated in obesity. AgRP shares sequence and structural homology with the Agouti protein and has similar expression patterns in both mouse and human.
It is also supsected to play a role in modulation of pain.
AgRP: Customer Publications
Image: Double-staining of Fos positive neurons with anti-AgRP in the DMH. Overview of doublestaining with anti-AgRP (A) and anti-Fos (B) in the DMH. Merge image of double-staining showed that Fos-ir positive neurons (green staining) were encircled in a network of AgRP-irpositive fibers (red staining) in the DMH (C). doi: 10.1016/j.brainres.2008.01.054.