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Neurotensin is a 13-amino acid neuropeptide involved in neurotransmission in the CNS and PNS. The neurotensin receptors (NTS or NTSRs) are transmembrane receptors that bind neurotensin. NTSR1 and NTSR2 contain seven transmembrane helices and are G protein coupled whereas NTSR3 has a single transmembrane domain.

Image: Immuofluorescent detection of NTSR1 in cell bodies of neurons in rat dorsal root ganglia (red fluorescence). Inset: NTSR3 staining of 1 day-old mouse cortical cell culture. Dilution-1:2000.

By selective targeting or blockade of specific neurotensin receptors, investigators have identified potential drugs for use in the treatment of schizophrenia, alcoholism, chronic pain, or cancer.

NameCatalog #TypeSpeciesApplicationsSizePrice
NeurotensinRA20072Rabbit IgGM; RIHC100 ul$245
Neurotensin Receptor 1 (NTS1)GP14020Guinea Pig IgGRICC; IHC50 ul
100 ul
100 ug Blocking Peptide
$190
$345
$95
Neurotensin Receptor 1 (NTS1)CH14110Chicken IgYRIHC100 ul
100 ug Blocking Peptide
$345
$95
Neurotensin Receptor 2 (NTS2)RA17100Rabbit IgGRICC; IHC100 ul$315
Neurotensin Receptor 3 (NTS3)/SortilinGT15237Goat IgGHIHC; WB; E; NB100 ug$365
Neurotensin Receptor 3 (NTS3)/SortilinGT15238Goat IgGMIHC; WB; E; NB100 ug$365
Neurotensin Receptor 3 (NTS3)/SortilinRA25040Rabbit IgGM; RICC; IHC; WB100 ul$385