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MO15109100 ug$255.00Buy Now | Add to Cart
 
Type: Mouse IgG
 
Applications: ICC; IHC; FC
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Protein G Purified - liquid
 
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with NS0 cells transfected with human SSTR2 (hSSTR2; aa 1 - 369; Accession # P30874).
 
Description/Data:
Picture

Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.

These SST Receptors function in the regulation of numerous phsiological processes such as the secretion of insulin, glucagon and growth hormone as well as cell growth induced by neuronal excitation in both the central and peripheral nervous systems.

Image: MDA-MB-231 cells were stained with anti-SSTR2 (filled histogram) or isotype control antibody (open histogram), followed by APC-conjugated anti-mouse antibody.

Other Reagents to Consider:

Somatostatin Receptor-2-SSTR2-Rabbit

Somatostatin Receptor-1-SSTR1

 

Autism/Asperger's Syndrome Antibodies

Autism/Asperger's Syndrome Proteins

Neurodegenerative Disease Antibodies

Neurodegenerative Disease Proteins

Pain and Inflammation

Diabetes and Obesity