NOGO Receptor

Affinty Purified Goat Antibody
DATASHEET(pdf - 37Kb)
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Type: Goat IgG
 
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Immunogen: Sf 21-derived, recombinant human Nogo Receptor (rhNgR), amino acid residues 27 - 447.
 
Description/Data:
Picture

NOGO Receptor (NgR) is a glycosylphosphatidylinositol (GPI)-anchored protein. It interacts with the p75 NGF receptor as a co-receptor for Nogo, oligodendrocyte myelin glycoprotein (OMgp) and myelin-associated glycoproteins (MAG) to transduce inhibitory signals for inhibition of neurite outgrowth (Wang, K.L. 2002, 74).

 

 

Image: Nogo Receptor staining in sections of paraffin-embedded human spinal cord. Tissues were stained with anti-goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

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