|Catalog Number||Size||Price (USD)||Shopping Cart|
|CH23002||100 ul||$99.00||Buy Now | Add to Cart|
Murine netrin-1 precursor is a 67,768 dalton protein (604 amino acids) expressed by subpopulations of cells within the developing CNS, as well as in various non-neural tissues, including the gut, liver, heart, and prostate. In the embryonic CNS, netrin-1 is expressed by cells of the floor plate, and acts to attract axons of commissural neurons from the dorsal horn gray matter. Netrin-1 is also believed to play a role in the growth of motor axons in the PNS.
Image: Dissociated cell cultures of an e13 mouse brain showing Netrin-1 (green staining) in neuronal precursor cells.
Netrin-1: Customer Publications
Primary Neurons and Astrocytes-Primary human, rat and mouse neurons and astrocytes by Category
Images: Immunohistochemical colocalization of netrin-1 and endothelial markers. Paraformaldehyde-fixed frozen tissue sections were stained with anti-netrin-1 antibody (red stain) and anti-Von Willebrand Factor (VWF) antibody (green stain) as described in MATERIALS AND METHODS. Nuclei were stained blue with DAPI. In sham-operated kidney (B–D), netrin-1 staining was mainly in the interstitium and colocalized with VWF. Similarly, netrin-1 and VWF colocalized in the kidney section from 72 h of reperfusion (E and F). No staining was seen in the primary antibody negative control (A). Colocalization of netrin-1 (red) and GFP (green) in kidney from Tie2-GFP mice was also observed under normal conditions (G and H). doi:10.1152/ajprenal.00508.2007.
Image: Immunohistochemical localization of netrin-1 in renal cell carcinoma (RCC) tissues. A. Secondary antibody control showing no staining. B. Normal adjacent tissues do not show any staining for netrin-1. C. Stage I RCC shows staining for netrin-1. D. Stage II RCC shows staining for netrin-1. E&F. doi: 10.3109/1354750X.2010.541564