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RA25081100 ul$395.00Buy Now | Add to Cart
 
Type: Rabbit IgG
 
Applications: ICC; IHC; IP; WB
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H; M; R
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Protein A purified - liquid
 
Immunogen: Recombinant mouse Olig2.
 
Description/Data:
Picture

Olig1 and Olig2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the motor neuron progenitor (pMN) domain of the spinal cord that generates motor neurons and oligodendrocytes. Olig1 is involved in the development andmaturation of oligodendrocytes. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord. 

Olig1 and 2 are also a markers for  the most common primary tumors of the human brain are thought to be of glial cell origin. Therefore, there is diagnostic potential of Olig markers to augment identification of oligodendroglial tumors.

Image:  Neonatal rat brain lysate showing specific immunolabeling of the ~ 32k Olig2 protein.