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GT15186100 ug$365.00Buy Now | Add to Cart
 
Type: Goat IgG
 
Applications: IHC; WB; E
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: Purified, E. coli-derived, recombinant human Hepatic Nuclear Factor 3 beta (rhHNF-3 beta 42 - 457).
 
Description/Data:
Picture

HNF-3 beta, also known as FoxA2 is a 48-kDa member of the HNF-3/forkhead class of DNA binding proteins. It is part of the Sonic Hedgehog (Shh) signaling pathway.

CD4-Foxa2+ GFP-Bry+ populations isolated from activin-induced Embryonic Stem Cells differentiation cultures is able to generate cells that display characteristics of hepatocytes. This gene has been linked to sporatic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.

Image: HNF-3β in human HepG2 cells.  Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody .

Picture[2]

Image: Hepatic Nuclear Factor-3 beta (HNF-3 beta)/FoxA2 was detected in immersion fixed endoderm differentiated BG01V human embryonic stem cells using Human HNF-3 beta Antigen Affinity-purified Polyclonal Antibody at 10 µg/mL for 3 hours at room temperature. Cells were stained using a 557-conjugated Anti-Goat IgG Secondary Antibody and counterstained with DAPI (blue).