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GT15189100 ug$365.00Buy Now | Add to Cart
 
Type: Goat IgG
 
Applications: ICC; WB; E
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: Purified, E. coli-derived, recombinant human tumor protein 63 (rhTP63; aa 1 - 300; Accession # NP_003713).
 
Description/Data:
Picture

This polyclonal anti-TP63 is predicted to recognize all isoforms of TP63, including TAp63, DeltaNp63, TP63α, β, γ, and δ. TP63, also named p63, TP73L, p51, p40 or KET, was originally identified as a p53 family member. It is highly expressed in embryonic ectoderm and in the nuclei of basal regenerative cells of many epithelial tissues in the adult including skin, breast myoepithelium, oral epithelium, prostate and urothelia. The expression of various TP63 isoforms has been suggested to play a role in development, epithelial cell maintenance and tumorigenesis.1 - 3

1. Courtois, S.  et al., 2004, Oncogene 23(3):631 - 638.
2. Koster, M.I. and D.R. Roop, 2004, J. Dermatol. Sci.  34(1):3 - 9.
3. Vincek, V.  et al., 2003, Anticancer Res. 23(5A):3945 - 3948.

 

 

 

 

Image: TP63 staining in human SSC-25 cells using. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody.

Other Reagents to Consider:

Cancer Antibodies

Cancer Proteins

Stem Cell Reagents