Network with Neuromics
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Neuromics
5325 West 74th St., Suite 8
Edina, MN 55439
Toll free: 866-350-1500
Int'l phone: 952-374-6161
Fax: 612-677-3976
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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| GT15219 | 100 ug | $365.00 | Buy Now | Add to Cart |
SMAD1 is a member of the Mothers Against Dpp (MAD)-related family of proteins. So far, eight SMADs have been identified and can be divided into 3 subgroups based on their structure and function; pathway-restricted, common mediator and inhibitory. SMAD1, 5 and 8 serve as pathway-restricted SMADs for the bone morphogenetic protein (BMP) signaling pathway.
Smad1 is phosphorylated resulting in its association with the common-mediator subunit, Smad4. This heteromeric complex then translocates into the nucleus to exert transcriptional comodulator activity.
Image: Detection of Smad1. Lysates from 5 x 105 human HepG2, MDA-MB-468, and HT29 cells were resolved by SDS-PAGE, transferred to Immobilon-P membrane, and immunoblotted with 0.5 μg/mL goat anti-Smad1 as described in Protocols for Immunoblotting. A 30 second exposure to film is shown.
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Neurotrophins-Neuron/Glial Marker Proteins Neurotrophins and Growth Factor Antibodies Apoptosis Research Reagents-Apoptosis Categories-includes: detection kits, antibodies and proteins |