TRAIL and TRAIL Receptors
Apoptosis or programmed cell death is induced in cells by a group of death domain containing receptors.
TRAIL binds at least five different receptors: TRAIL R1 (DR4), R2 (DR5), R3 (DcR1), R4 (DcR2), and osteoprotegerin (OPG). TRAIL receptors all exhibit cysteine-rich repeats characteristic of the TNF receptor superfamily. TRAIL R1 and R2 are type 1 transmembrane proteins with intracellular death domains (DD) and, subsequently, have the ability to mediate TRAIL-induced apoptosis.
|TRAIL||GT15060||Goat IgG||H||ICC; WB; E||50 ug|
|TRAIL R1/CD261||GT15061||Goat IgG||H||IHC; WB; E||100 ug||$365|
|TRAIL R3/CD263||GT15062||Goat IgG||H||IHC; WB; E||50 ug|
|TRAIL R4/CD264||GT15063||Goat IgG||H||IHC; WB; E||100 ug||$365|