Vasopressin V1B Receptor

Affinity Purified Goat Antibody
DATASHEET(pdf - 105Kb)
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Type: Goat IgG
 
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Immunogen: Synthetic peptide: Peptide with sequence C -PRDLELADGEGTAE, from the C Terminus of the protein sequence according to NP_000698.1.
 
Description/Data:
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Arginine vasopressin (AVP) is a neurohypophysial hormone found in most mammals, including humans. It is invlolved in regulating mood.

Antogonists of Vasopressin V1B Receptor (AVPR1B) has been found to protect against depression. It has also been theorized that it might play a role in anxiety disorders as well as in unipolar depression.

Image: AVPR1B (dilution: 5µg/ml) staining of paraffin embedded Human Anterior Pituitary Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

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Image :AVPR1B (dilution: 0.5µg/ml) staining of Human Amygdala lysate (35µg protein in RIPA buffer) in lane A and  staining of Rat Brain lysate in lane B . Primary incubation was 1 hour. Detected by chemiluminescence