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MO15097100 ug$255.00Buy Now | Add to Cart
 
Type: Mouse IgG
 
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H; R
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Protein G Purified - liquid
 
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, E. coli-derived, recombinant human Calbindin D (rhCalbindin D; aa 1 - 261; Accession # P05937).
 
Description/Data:
Picture

Calbindin-D, also known as Calbindin 1, is a Vitamin D-dependent cytoplasmic protein in the EF-hand calcium binding protein family that includes calmodulin, parvalbumin, troponin C, and S100. Calbindin-D is widely expressed and regulates calcium homeostasis. Calbindin-D protects neurons from excitotoxic and apoptotic cell death by buffering excess calcium. Human, mouse, and rat Calbindin-D share 99% amino acid sequence identity.

Images: Calbindin D staining of  paraffin-embedded human cerebellum and frozen rat hypothalamus sections using 25 µg/mL mouse anti-human Calbindin D monoclonal antibody. Tissues were stained using anti-mouse HRP-DAB ( brown) and counterstained with hematoxylin (blue).

Picture[2]

Image: Calbindin D staining of  paraffin-embedded rat brainstem medulla. Staining is shown in the medial vestibular nucleus using 25 µg/mL mouse anti-human Calbindin D monoclonal antibody. Tissue was stained anti-mouse HRP-AEC and counterstained with hematoxylin (blue).