Network with Neuromics
Contact Information
Neuromics
5325 West 74th St., Suite 8
Edina, MN 55439
Toll free: 866-350-1500
Int'l phone: 952-374-6161
Fax: 612-677-3976
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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| GT15192 | 100 ug | $365.00 | Buy Now | Add to Cart |
SMAD5 is a member of the Mothers Against Dpp (MAD)-related family of proteins. So far, eight SMADs have been identified and can be divided into 3 subgroups based on their structure and function; pathway-restricted, common mediator and inhibitory. SMAD1, 5 and 8 serve as pathway-restricted SMADs for the bone morphogenetic protein (BMP) signaling pathway. SMAD5 is directly activated by BMP type Ia or Ib receptors upon BMP-2 stimulation and transduced BMP-2 signals to the nucleus by forming a complex with SMAD4.
Smad5 could be a marker for several forms of cancer inluding colo-rectal.
Image: SMAD5 staining paraffin-embedded human colon tissue sections (dilution 5 µg/mL). Tissues were stained usiing anti-goat HRP-DAB (brown) and counterstained with hematoxylin (blue).
More Links:
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BMP (Bone Morphogenetic Proteins) Proteins Neurotrophins and Growth Factor Antibodies Neuron-Glial Expressed-Includes Neurotrophin Proteins |
Apoptosis Research Reagents-Apoptosis Categories-includes: detection kits, antibodies and proteins |