The endoderm is one of the three primary germ cell layers in the very early embryo. This germ layer gives rise to the epithelial lining of the body's two major tubes, the digestive tract and the respiratory tract. The mouth and rectum form following involutions of the ectoderm. Endocrine glands which open into the digestive tube also originate from the endoderm, including cells for the liver, pancreas, and gall bladder.

Image: SOX17 staining of endodermal cells derived from human embyronic stem cells. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody and counterstained using Fluoro Nissl (green). Courtesy of Dr. Jong-Hoon Kim and Dr. Ron McKay from the National Institute of Neurological Disorders and Stroke & Stem Cell Unit at NIH.

Endodermal lineage marker uses include study of primitive definitive endoderm, as well as pancreatic, hepatic, and endocrine progenitor cells.

NameCatalog #TypeSpeciesApplicationsSizePrice
5T4GT15239Sheep IgGMICC; WB; FC; E100 ug$365
GDF-3GT15176Goat IgGMIHC; WB; E100 ug$365
HNF-3beta/FoxA2GT15186Goat IgGHIHC; WB; E100 ug$365
PDX1/IPF1GT15187Goat IgGHIHC; WB; E100 ug$365
SOX7MO15050Mouse IgGHWB; E100 ug
50 ug
SOX17GT15094Goat IgGHICC; WB; E100 ug$365