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Semaphorins are a class of secreted and membrane proteins that act as axonal growth cone guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric receptor complexes. They are usually cues to deflect axons from inappropriate regions, especially important in neural system development. The major class of proteins that act as their receptors are called plexins.

Two distinct transmembrane receptor families have been identified as Semaphorin receptors. Neuropilins provide binding specificity for the class 3 Semaphorins, whereas Plexins, which also contain a Sema domain serve as signaling partners for class 3 Semaphorins and as functional receptors for transmembrane Semaphorins.

NameCatalog #TypeSpeciesApplicationsSizePrice
Plexin A3GT15211Goat IgGH; M; RIHC; WB; E100 ug$365
Semaphorin 3BRA25088Rabbit IgGB; D; H; M; Pr; RICC; IF; IHC; WB50 ul$325
Semaphorin 3CGT15077Sheep IgGMIHC; WB; E100 ug$365
Semaphorin 5AGT41026Goat IgGHIHC100 ug
100 ug Blocking Peptide
$250
$145
Semaphorin 6AGT15056Chicken IgY100 ug$365
Semaphorin 6AMO15023Rat IgGMIHC; WB; E500 ug$325
Semaphorin 6BGT15165Goat IgGH; MIHC; WB; E100 ug$365
Semaphorin 7AGT15076Goat IgGMWB; E50 ug$365
Semaphorin 7AMO15041Rat IgGH; MWB; E500 ug
100 ug
50 ug
$325
$89
$49