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RA3004150 ug$425.00Buy Now | Add to Cart
 
Type: Rabbit IgG
 
Applications: IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Immunogen: Synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP, which differ from the mouse sequence by three amino acids (7-9).
 
Description/Data:
Picture
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. PERP (TP53 Apoptosis Effector) is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family. 

Image: PERP staining of Human Skin: Formalin-Fixed Paraffin-Embedded (FFPE).

Other Reagents to Consider:

PARC Antibody

PUMA Antibody 

Tumor Protein P53 (TP530) Antibody

TP63/TP73l Antibody

All Apoptosis Reagents

Apoptosis Research Antibodies

Apoptosis Research Proteins

Cancer Research Antibodies

Cancer Research Proteins