Network with Neuromics
Contact Information
Neuromics
5325 West 74th St., Suite 8
Edina, MN 55439
Toll free: 866-350-1500
Int'l phone: 952-374-6161
Fax: 612-677-3976
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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| PR27070-2 | 2 ug | $85.00 | Buy Now | Add to Cart |
| PR27070-10 | 10 ug | $175.00 | Buy Now | Add to Cart |
Type: Protein
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Immunogen: a single, glycosylated, polypeptide chain containing 127 amino acids and having a molecular mass of 26-32 kDa. rhGMCSF differs from the natural human GM-CSF by a substitution of leucine at position 23 (R to L), and the carbohydrate moiety may be different from the native protein.
Description/Data:
GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes